Details for gene set BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos
Phenotype	phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos
Upregulated in class	wtNotch
GeneSet	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Enrichment Score (ES)	-0.75364137
Normalized Enrichment Score (NES)	-1.4432946
Nominal p-value	0.06300813
FDR q-value	0.5886167
FWER p-Value	1.0

Fig 1: Enrichment plot: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTPRC	130402 5290148	2759	0.346	-0.1076	No
2	FYN	2100468 4760520 4850687	2920	0.311	-0.0796	No
3	CD247	3800725 5720136	3658	0.193	-0.0965	No
4	LCK	3360142	15886	-0.337	-0.7140	Yes
5	CD4	1090010	16529	-0.501	-0.6896	Yes
6	CD3E	3800056	17288	-0.783	-0.6383	Yes
7	TRB@	3940292	17711	-1.000	-0.5433	Yes
8	ZAP70	1410494 2260504	17916	-1.139	-0.4204	Yes
9	CD3G	2680288	18361	-1.692	-0.2452	Yes
10	CD3D	2810739	18534	-2.201	0.0044	Yes

Fig 2: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION: Random ES distribution
Gene set null distribution of ES for BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION